Tamas E. Gunda
Hungarian
About myself in one sentence:
My name is Tamas E. Gunda, I was born in Kolozsvár. I am married and have got two children, Lenard and Cynthia
* University of Debrecen
H-4010 Debrecen, P.O.Box 70
Hungary
( (+36 52) 512 900 / 22472, 22479
fax: (52) 512 914
E-mail: tgunda2 {AT} puma·unideb·hu
Education:
1972 – Diplom of Chemistry (M.A.) at L. Kossuth University, Debrecen, Hungary.
1976 – University Doctor degree ( Thesis: The ring expansion of penicillin sulfoxides to cephalosporins)
1984 – Ph.D. (Thesis: Preparations of cephalosporins and other β-lactam derivatives from penicillin)
2000 – Doctor of the Hungarian Academy of Sciences (D. Sc.)
Professional carreer:
1972 – 1985 Research fellow and research associate at the Research Group for Antibiotics of the Hungarian Academy of Sciences, situated at the University of Debrecen, Debrecen, Hungary
1985 – 1989 R&D senior chemists, Fermion Pharmaceutical Works, Orion Corporation Ltd, Espoo, Finland
1989 – Senior research associate and privatdozent at the Research Group for Antibiotics of the Hungarian Academy of Sciences.
2001 – Professor
2005 – Full professor, Institute of Pharmaceutical Chemistry, Medical and Health Center, University of Debrecen.
The Research Group of Antibiotics of the Hungarian Academy of Sciences is situated at the University of Debrecen, Debrecen, Hungary. Its main research field is the chemistry of antibiotics and chemotherapeutics, chemically mainly carbohydrates and/or heterocyclic compounds. I am dealing here with organic and drug chemistry, first and foremost with the ß-lactam antibiotics.
Longer professional visits:
- 1975 – 1976 1/2 year in Warsaw, Poland, Inst. of Organic Chemistry, Polish Academy of Sciences, as research fellow on the field of steroids;
- 1979 – 1980 9 months in Helsinki, Finland, Technical University of Helsinki, Institute of Organic Chemistry, as postdoc research associate, on the field of tricyclic benzodiazepines condensed with β-lactam ring.
- Between 1985-1989 at Fermion Pharmaceutical Works, Orion Corporation Ltd, Helsinki, I was dealing with antibacterial agents of guanidin and biguanidin-type, as well as with the organization of chemical data bases.
Main fields of interest:
The synthesis of new cephalosporin analogs with condensed bi- or tricylic ring systems, mainly with Diels-Alder cycloaddition reactions.
The synthesis of new 2-substituted cephalosporin derivatives possessing ß-lactamase or HLE enzym inhibitory properties.
Structure-activity relationships of the ß-lactam antibiotics.
Use of computer aided molecular modelling in drug design; molecular mechanics and dynamics; microcomputers and information systems in organic chemistry and drug design. Molecular modelling to solve stereochemical or other theoretical problems in organic chemistry. This led to the development of the software Mol2Mol.
Microcomputers and information systems in organic chemistry and drug design.
My hobbies are books, computers and Finland
Educational activity:
I used to lead the organic chemistry or pharmaceutical chemistry laboratory exercises of students, as well as I am a tutor of students writing their B.A. or M.A. thesis, and the supervisor of postgrads making their Ph.D. thesis. I am regularly lecturing in special topics (Selected topics from molecular drug chemistry; Basics of molecular modelling and chemical databases).
tgunda2 {AT} puma·unideb·hu
Department of Chemistry Department of Pharmaceutical Chemistry
University of Debrecen
Department of Chemistry
